Antibody Ige Was Produced From

Description: The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. Wiskott-Aldrich syndrome is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia, and is caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in WAS patients. A transcript variant arising as a result of alternative promoter usage, and containing a different 5' UTR sequence, has been described, however, its full-length nature is not known.

Description: A polyclonal antibody against Phospho-WAS (Y290). Recognizes Phospho-WAS (Y290) from Human, Mouse. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/5000

Description: A polyclonal antibody against WAS. Recognizes WAS from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

Description: A polyclonal antibody against WAS. Recognizes WAS from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

Description: A polyclonal antibody against WAS. Recognizes WAS from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human WAS (Center). This antibody is tested and proven to work in the following applications: